Description
Product Overview
The Cobetter MCE gridded membrane filter is engineered for precise microbiological testing, offering a 47 mm diameter and a 0.45 μm pore size that captures bacteria while allowing rapid fluid passage. Constructed from a mixed cellulose ester blend of nitrocellulose and cellulose acetate, the membrane provides a smooth, flat surface that enhances colony visibility and improves recovery rates. Each filter is pre‑sterilized using a 25 kGy gamma radiation dose, ensuring a contaminant‑free starting point for critical assays. The filters are individually sealed in sterile packaging, protecting them from environmental exposure until the moment of use. Their hydrophilic nature eliminates the need for wetting agents, simplifying preparation and reducing the risk of sample dilution.
Key specifications include a maximum operating temperature of 130 °C, 75 % porosity for high flow rates, and a robust 3 mm grid pattern that enables accurate colony enumeration without compromising growth. The product complies with ISO 9001:2008 standards and meets current Good Manufacturing Practice (cGMP) requirements, reflecting Cobetter’s commitment to quality and regulatory adherence. The 100‑pack configuration offers laboratories a cost‑effective solution for routine testing, validation studies, and large‑scale production monitoring, ensuring consistent performance across multiple experiments.
Beyond its technical attributes, the filter’s design facilitates ease of handling. The rigid 47 mm frame fits standard filtration apparatus, and the clear grid lines are printed directly onto the membrane, eliminating the need for external templates. This integration reduces setup time and minimizes user error, making the filter suitable for both experienced microbiologists and technicians new to membrane filtration techniques. The combination of high flow capacity, reliable sterility, and precise grid alignment positions this product as a versatile tool for a wide range of microbiological investigations.
Usage
In pharmaceutical quality control labs, the filter is ideal for sterility testing of injectable solutions, where rapid detection of microbial contamination is essential. Its 0.45 μm pore size captures a broad spectrum of bacteria, while the high flow rate shortens filtration time, allowing more samples to be processed within tight production schedules. The clear grid lines support quantitative colony counting, enabling compliance with pharmacopeial limits and facilitating documentation for regulatory submissions.
Environmental monitoring programs benefit from the filter’s durability and ease of use. When sampling air or water in cleanroom environments, the membrane’s hydrophilic surface ensures uniform distribution of captured particles, improving the reliability of microbial load assessments. The pre‑sterilized packaging eliminates the need for additional decontamination steps, reducing the risk of introducing external contaminants during field sampling.
Academic research laboratories conducting microbiome studies or biofilm investigations also find value in the filter’s consistent performance. The mixed cellulose ester composition supports the growth of a wide variety of microorganisms, allowing researchers to observe colony morphology and conduct downstream analyses such as PCR or sequencing directly from the membrane. The filter’s compatibility with standard incubators and its resistance to temperature fluctuations make it a dependable component in long‑term experimental protocols.
Why Choose Us
Cobetter’s reputation for quality is reinforced by rigorous manufacturing controls and a dedicated quality assurance team. Every batch of filters undergoes comprehensive testing for pore size uniformity, flow rate consistency, and sterility assurance levels, ensuring that customers receive products that meet or exceed industry expectations. The company’s ISO 9001:2008 certification underscores its systematic approach to continuous improvement, while adherence to cGMP guidelines guarantees that the filters are suitable for regulated environments.
Customer support extends beyond product delivery. Cobetter provides technical assistance for method development, troubleshooting, and validation documentation, helping laboratories integrate the filters seamlessly into existing workflows. A responsive service team is available to address inquiries, supply usage guidelines, and offer training resources, ensuring that users achieve optimal results from the first filtration to routine quality checks.
Key Features
- Pre‑sterilized by 25 kGy gamma radiation for immediate, contaminant‑free use.
- High flow rate and 75 % porosity reduce filtration time and increase sample throughput.
- Clear 3 mm grid lines printed on the membrane enable accurate colony counting without additional tools.
- Mixed cellulose ester composition offers excellent bacterial recovery and supports diverse microbial growth.
- Dedicated technical support and documentation to assist with method validation and regulatory compliance.
FAQ
What is the recommended storage condition for the filters?
The filters should be stored in a dry, temperature‑controlled environment between 2 °C and 30 °C. Keep the packaging sealed until use to maintain sterility and prevent moisture absorption, which could affect pore performance.
Can the filters be used with solvents other than aqueous solutions?
Yes, the mixed cellulose ester membrane is compatible with a range of organic solvents commonly used in laboratory filtration, such as ethanol, methanol, and isopropanol. However, it is advisable to perform a compatibility test for any new solvent to ensure that the membrane integrity and pore size remain unchanged.
How do I verify the sterility of a filter before use?
While the filters are supplied sterile, laboratories often perform a sterility check as part of their validation protocol. This can be done by filtering a sterile growth medium, incubating the filter under appropriate conditions, and confirming the absence of microbial growth. The clear grid lines aid in visual inspection during this verification step.
What equipment is required to mount the 47 mm filter?
The filter fits standard vacuum filtration manifolds and syringe filter holders designed for 47 mm membranes. Ensure that the holder provides a tight seal to prevent leakage and that the filtration apparatus is compatible with the filter’s maximum temperature rating of 130 °C.
Is the filter suitable for high‑throughput automated filtration systems?
Yes, the filter’s dimensions and robust packaging make it compatible with many automated platforms that handle 47 mm membranes. The pre‑sterilized, individually sealed format simplifies loading and reduces the risk of cross‑contamination in high‑volume testing environments.
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